Making Human Eggs from Stem Cells

Making Human Eggs from Stem CellsBy Kristin Bendikson Researchers from Massachusetts General Hospital have claimed to generate new eggs cells from human ovarian stem cells. This groundbreaking research team, led by biologist Jonathan Tilly, was published online this past Sunday in the journal Nature Medicine. If validated, this research has the potential to open up a new field of reproductive biology that could have tremendous impacts on the field of infertility. Women are born with a finite number of eggs in their ovaries. As a woman ages, the number and quality of eggs diminishes. The loss of eggs is a...

Read More

IVF: If at first you don’t succeed, should you try again…

In vitro fertilization (IVF) is currently the most effective treatment available for infertility of nearly all causes. It is a very precise and controlled process, which involves stimulating the growth of multiple eggs, removal of the eggs from the ovaries (egg retrieval), fertilization in the embryology laboratory, and subsequent placement of the best-quality embryos into the uterus (embryo transfer). Despite continuing improvements in the technology, unfortunately there are times when IVF is not successful on the first or second try. While the devastation that often accompanies a negative pregnancy test after IVF is completely natural, it is important to understand...

Read More

A Woman’s Biological Clock and Fertility

In the mid-1980s, a group of scientists first discovered that there was a natural decrease in fertility as a woman aged. By studying different populations from as early as the 1600s (when contraception was not an option), these scientists were able to show that fertility rates declined gradually as the age of the female partner increased between 20 and 35—and then fell briskly after about the age of 37. By age 45, nearly all women were no longer fertile. In the setting of fertility treatment, this same pattern of age-related decline is seen. Even with the use of aggressive fertility...

Read More

Back to Basics: The Difference Between IUI and IVF

Intrauterine insemination (IUI) and in vitro fertilization (IVF) are two commonly used methods of fertility treatment, which increase a couple’s chance of becoming pregnant. IUI is a procedure during which processed and concentrated motile sperm are inserted directly into a woman’s uterus. This procedure is timed according to a woman’s ovulation, and may be performed one to two times in the days immediately following the detection of ovulation. After ovulation a woman’s egg is picked up by the fallopian tube and waits there for the sperm. Since the IUI procedure deposits higher concentrations of good quality sperm close to where...

Read More

Older Moms and Autistic Kids

Every week it seems that a new study pertaining to autism is being published. It’s not surprising considering that the Centers for Disease Control and Prevention has estimated that one in 110 children had the condition in 2006. The second week of February was no different. A research study from the University of California Davis published in the February issue of “Autism Research” examined the effect of maternal and paternal age on the risk of autism. This 10-year study examined 4.9 million births in the 1990s and found evidence to correlate an increased risk of autism with both increasing maternal...

Read More

Ethnicity and IVF

How a patient’s ethnic background affects her chance of pregnancy, especially with IVF, is a fascinating yet poorly studied area of research. According to a 1995 national survey of family growth, non-Caucasian married women were more likely to experience infertility than Caucasian married women, yet these same non-Caucasian women were less likely to receive any type of infertility treatment—especially treatment with assisted reproductive technologies. There is very little data in the literature examining ethnicity and its affect upon pregnancy rates with in vitro fertilization (IVF). Ethnic minorities compose a small percentage of patients in the nation’s IVF programs, making it...

Read More

Dr. Michael Kamrava and the Octuplets

Well, it has finally happened. The infamous octomom fertility specialist, Dr. Michael Kamrava, has been formally charged with negligence by the California Medical Board. The case has been handled as a type of sideshow by the media, and indeed, there are many aspects of it—single mom, 14 kids from IVF, all conceived with donor sperm, etc.—that seem stranger than fiction. However, responsible fertility specialists have taken this case very seriously. An octuplet pregnancy is a significant complication of fertility care. Since we are aware of this possible severe scenario, we take very strong measures to try to avoid situations in...

Read More

5 Things You Should Know About Polycystic Ovary Syndrome (PCOS)

1. PCOS is a Common ConditionPCOS is one of the most common causes of irregular menstrual periods. It’s a chronic condition that occurs in about 5 to 10 percent of women. It causes irregular menstrual periods and high levels of male hormones in women. These elevated levels can cause excessive hair growth in areas such as the face and back, and can cause male-pattern balding or thinning of hair. These hormones can also cause severe acne. Although PCOS is not completely reversible, there are several treatments that can improve these symptoms so that most women with PCOS are able to...

Read More